The main side effects of the patch form for depression include applicationsite reactions, insomnia, diarrhea, and sore throat. Although not all of these side effects may occur, if they do occur they may need medical attention. Nov 09, 2018 selegiline side effects get emergency medical help if you have signs of an allergic reaction. Emsam selegiline dose, indications, adverse effects. Transdermal selegiline for the treatment of major depressive. Feb 15, 2008 selegiline transdermal patch emsam patch with a dose of 6 mg per 24 hours applied each day. Concurrent use with tricyclic antidepressantsmay result in asystole,diaphoresis,hypertension,syncope,behav. When selegiline skin patch is used at low doses, there are no restrictions on the food or beverages that you can eat or drink. The discontinuation rate due to adverse effects was low, 6. Selegiline transdermal patch emsam for major depressive. Emsam is believed to work by changing the balance of neurotransmitters in the brain.
By blocking the action of monoamine oxidase in the brain, the medication can help improve the symptoms of depression. In clinical trials, approximately twice as many patients on transdermal selegiline 7 percent discontinued treatment because of adverse effects. Side effects can include insomnia, weight loss, and headaches. This dermatological side effect was usually of mild severity in the emsam clinical trials, rarely leading to discontinuing of medication. Commonly reported side effects of selegiline include. Side effects of emsam selegiline transdermal system, warnings. Side effects of emsam selegiline transdermal system. Emsam is a medication that comes in the form of a transdermal patch that treats depression in those 12 years and older. Remove the patch and seek medical attention right away if you have symptoms of serotonin syndrome, such as. What is the most important information i should know about selegiline transdermal emsam. Remove your old selegiline patch and apply a new patch at around the same time every day. Your condition will not improve any faster and your risk of side effects will increase. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to the side effects that occurred in another group of people taking a placebo a sugar pill that does not contain any active ingredients. Along with its needed effects, a medicine may cause some unwanted effects.
Selegiline may also be used for purposes not listed in this medication guide. Emsam selegiline transdermal system side effects, images. Adverse reactions occurring at an incidence of 2% or more among. Emsam selegiline transdermal system product characteristics. You should not use selegiline if you have an adrenal gland tumor or if you are using certain other medicines. Jul 26, 2017 our emsam selegiline transdermal system side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
Ways to cope with the side effects of parkinsons drugs. Jul 26, 2017 eating tyramine while you are using selegiline can raise your blood pressure to dangerous levels which could cause lifethreatening side effects. Transdermal selegiline comes as a patch to apply to the skin. An introduction to emsam side effects as with any medicine, there are possible side effects with emsam selegiline transdermal patch. You may report side effects to the fda at 18003321088. It is usually applied once a day and left in place for 24 hours. This is not a complete list of side effects and others may occur. Side effects of selegiline parkinsons disease home page. An overview of emsam sexual side effects emsam selegiline transdermal patch is a prescription medication that is used for the treatment of depression.
It is used with levodopacarbidopa in the treatment of parkinsons disease. It is usually added to therapy when there is a decrease in response to levodopa. Tell your doctor if any of these symptoms are severe or do not go away. Selegiline prevents the breakdown of chemicals in the brain that are often imbalanced in people with depression. Common side effects of the selegiline transdermal patch the selegiline transdermal patch has been studied thoroughly in clinical trials.
Selegiline has been thoroughly studied in clinical trials. Stop using selegiline and get medical help right away if any of these very serious side effects occur. See below for a comprehensive list of adverse effects. Call your doctor if you have any unusual problems while you are taking this medication. See what others have said about selegiline, including the effectiveness, ease of use and side effects.
However, not everyone who takes emsam will experience side effects. Selegiline oral eldepryl side effects, medical uses, and. Oct 06, 2014 this dermatological side effect was usually of mild severity in the emsam clinical trials, rarely leading to discontinuing of medication. Emsam is an antidepressant of the monoamine oxidase inhibitor maoi class. However, the chance exists that dangerous reactions, such as sudden high blood pressure, may occur if higher doses are used with certain foods or beverages. Selegiline transdermal route precautions mayo clinic. If you have questions about side effects, call your doctor. In clinical trials with selegiline odt, the mean reduction of off time was. Selegiline is an enzyme blocker mao inhibitor that works by slowing the breakdown of certain natural substances in the brain neurotransmitters such as dopamine, norepinephrine, and serotonin. Selegiline skin patch may cause some people to be agitated, irritable, or display other abnormal behaviors.
Dose reductions of levodopa may be needed if dopaminergic side effects, including dyskinesia and hallucinations emerge. Selegiline should be discontinued 2 wk before ssris are initiated. Emsam selegiline transdermal uses, side effects, dosage. Side effects of the pill form of emsam may include confusion, depression, nausea, insomnia, hallucinations, poor balance, involuntary muscle movements, slow or irregular heart rate, delusions, chest pain, and syncope fainting. Selegiline is an enzyme blocker mao inhibitor that works by slowing the breakdown of certain natural substances in the brain neurotransmitters such as. Sideeffects of levodopa may be increasedconcurrent levodopa dosage can be reduced by 1030% in steps of 10% every 34 days. In clinical trials with selegiline transdermal patches, application site reaction was reported as the side effect that lead to treatment. Jan 24, 2020 people using selegiline may be at increased risk of experiencing high blood pressure if they consume too much tyramine 6 mg so talk to your doctor about possibly cutting back on these foods if you are taking selegiline 62, 64.
Selegiline hydrochloride drug bnf content published by. You may report side effects to health canada at 18662342345. Each time you apply a new patch, use a new area of skin on the upper back, upper chest, upper thigh, or to the outer part of the upper arm. Selegiline transdermal is used to treat major depressive disorder in adults. You should become very familiar with the list of foods to avoid while you are using selegiline 9mg or 12mg patches. Do not apply more patches or leave the patch on for longer than prescribed. Jan 28, 2020 side effects not requiring immediate medical attention.
It is part of a group of medications called monoamine oxidase inhibitors maois. Emsam selegiline transdermal system emsam 6 mg9 mg12 mg. Selegiline hydrochloride drug bnf content published by nice. Emsam selegiline prevents the breakdown of chemicals in the brain that are often imbalanced in people with depression. This would minimize side effects and thus allow patients to more easily tolerate. The effect of direct heat applied to the emsam patch on the bioavailability of selegiline. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not.
Like other moa blockers, selegiline can have mildtosevere side effects, such as 4, 65. The selegiline patch carries a black box warning about a possible increased risk of suicide, especially for young people, 7 as do all antidepressants since 2007. Patients receiving 10 mg conventional selegiline hydrochloride tablets can be switched to oral lyophilisates zelapar 1. Since maois affect brain chemistry, not following the doctors recommendations will make it more likely for the patient to suffer severe side effects. Selegiline may help people with parkinsons disease by decreasing the dose of levodopacarbidopa needed to control symptoms, stopping the effects of levodopacarbidopa from wearing off between doses, and increasing the length of time that levodopacarbidopa will continue to control symptoms. Selegiline transdermal patch mental health home page. The selegiline transdermal patch is a prescription medicine approved for the treatment of depression in adults. Common side effects of the patch include insomnia, sore throat, diarrhea, and agitation of the skin at the patch site.
Some side effects may occur that usually do not need medical attention. Part of the ldeprenyl hydrochloride, also called selegiline hydrochloride, family of prescription medications, anipryl is used to treat canine cognitive dysfunction ccd and certain forms of cushings disease. Eating tyramine while you are using selegiline can raise your blood pressure to dangerous levels which could cause lifethreatening side effects. Emsam selegiline transdermal system is an antidepressant used to treat major depressive disorder in adults. It is used with levodopa carbidopa in the treatment of parkinsons disease.
These are not all of the side effects that may occur. As with all medicines, emsam has possible side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Selegiline transdermal route side effects mayo clinic. Selegiline side effects, dosage, interactions drugs. In canada call your doctor for medical advice about side effects. Get information on selegiline, transdermal patch including uses, dosage details, medication sideeffects and drug interaction facts from cleveland clinic s health library. Some side effects of selegiline may occur that usually do not need medical attention.
Hypertension is predicted to occur when highdose selegiline is taken with tyraminerich foods such as mature cheese, salami. Signs symptoms and side effects of emsam selegiline abuse misusing selegiline or taking a different amount than prescribed can lead to serious side effects. The selegiline patch carries a black box warning about a possible increased risk of suicide, especially for young people, 7 as. This medication works by working with the chemicals in the brain to keep them stabilized. Selegiline oral eldepryl side effects, medical uses. This medication must not be used in children younger than 12 years due to an increased risk of serious side effects such as extremely high blood pressure. Before taking selegiline, tell your doctor or pharmacist if you are allergic to it. Selegiline side effects get emergency medical help if you have signs of an allergic reaction. Selegiline is a medicine licensed to treat parkinsons disease. These side effects may go away during treatment as your body adjusts to the medicine. You may report side effects to your national health agency. Call your doctor for medical advice about side effects.